Publicist Stan Rosenfield gave no other details of the 45 year old's condition.
But the celebrity reports website TMZ reported Mr Sheen was taken by ambulance from his home following an early morning emergency call.
Mr Sheen currently stars in the fashionable TV comedy Two and a Half Men. He also starred in the films Wall Street, Major union and Platoon.
TMZ reported, His father, Hollywood star Martin Sheen, mother, and ex wife were with him at Cedars Sinai Hospital in Los Angeles.
Charlie Sheen filed for divorce from his third wife, Brooke Mueller, in November, citing incompatible differences.
In late October 2009 the actor was accused of causing injure to a hotel room in New York.
After hotel security reported Mr Sheen was unmanageable, the actor voluntarily went with authorities for a psychiatric evaluation.
However, Mr Sheen's publicist said the actor had gone to hospital because he had "an unfavorable allergic reaction to some medicine".
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